2024
McTavish PV, Mutch DM. 2024. Omega-3 fatty acid regulation of lipoprotein lipase and FAT/CD36 and its impact on white adipose tissue lipid uptake. Lipids Health Dis; 23 (1): 386.
Maitland SB, Brauer P, Mutch DM, Royall D, Klein D, Tremblay A, Rheaume C, Jeejeebhoy K. 2024. Exploratory analysis of the variable response to an intensive lifestyle change program for metabolic syndrome. BMC Prim Care; 25 (1): 357.
MacLeod B, Wang C, Brown LH, Borkowski E, Nakamura MT, Wells KRD, Brunt KR, Harasim-Symbor E, Chabowski A, Mutch DM. 2024. Fads2 knockout mice reveal that ALA prevention of hepatic steatosis is dependent on delta-6 desaturase activity. J Lipid Res; 65 (10): 100642.
Budd JM, Notaro NM, MacLeod B, Mutch DM, Dyck DJ. 2024. A ketogenic diet, regardless of fish oil content, does not affect glucose homeostasis or muscle insulin response in male rats. Am J Physiol Endocrinol Metab; 327 (4): E449-458.
Loukil I, Mutch DM, Plourde M. 2024. Genetic association between FADS and ELOVL polymorphisms and the circulating levels of EPA/DHA in humans: a scoping review. Genes Nutr; 19 (1): 11.
Jannas-Vela S, Candia AA, Peñailillo L, Barrios-Troncoso P, Zapata-Urzúa J, Rey-Puente J, Aukema HM, Mutch DM, Valenzuela R, Valladares-Ide D. 2024. Role of specialized pro-resolving mediators on inflammation, cardiometabolic health, disease progression, and quality of life after omega-3 PUFA supplementation and aerobic exercise training in individuals with rheumatoid arthritis: a randomized 16-week, placebo-controlled interventional trial. F1000Res; 12: 942.
Metherel AH, Valenzuela R, Klievik BJ, Cisbani G, Rotarescu RD, Gonzalez-Soto M, Cruciani-Guglielmacci C, Layé S, Magnan C, Mutch DM, Bazinet RP. 2024. Dietary docosahexaenoic acid (DHA) downregulates liver DHA synthesis by inhibiting eicosapentaenoic acid elongation. J Lipid Res; 65 (6): 100548.
2023
MacIntyre BC, Shanmuganathan M, Klingel SL, Kroezen Z, Helmeczi E, Seoh NY, Martinez V, Chabowski A, Feng Z, Britz-McKibbin P, Mutch DM. 2023. Urinary Metabolite Profiling to Non-Invasively Monitor the Omega-3 Index: An Exploratory Secondary Analysis of a Randomized Clinical Trial in Young Adults. Metabolites; 13 (10): 1071.
Medak KD, McKie GL, Peppler WT, Shamshoum H, Dibe HA, Mutch DM, Josse AR, Wright DC. 2023. Liver triacylglycerol accumulation but not postprandial lipemia is reduced by a skim milk powder diet in male rats. Nutr Res; 119: 65-75.
Ly R, MacIntyre BC, Philips SM, McGlory C, Mutch DM, Britz-McKibbin P. 2023. Lipidomic studies reveal two specific circulating phosphatidylcholines as surrogate biomarkers of the omega-3 index. J Lipid Res; 64 (11): 100445.
Hatherell J, Abdelmagid SA, Ma DWL, El-Sohemy A, Mutch DM. 2023. Dietary and plasma retinoids are not associated with fatty acid desaturase indices in healthy young adults. Lipids; 58 (5): 217-227.
Wang C, Hucik B, Sarr O, Brown LH, Wells KRD, Brunt KR, Nakamura MT, Harasim-Symbor E, Chabowski A, Mutch DM. 2023. Delta-6 desaturase (Fads2) deficiency alters triacylglycerol/fatty acid cycling in murine white adipose tissue. J Lipid Res; 64 (6): 100376.
Gonzalez-Soto M, Woods SE, MacLeod B, Wright DC, Mutch DM. 2023. A moderate-fat diet containing soy protein does not differentially impact energy balance in male and female mice compared to dairy protein. Nutr Res; 113: 59-65.
Budd JM, Hucik B, Wang C, King AN, Sarr O, Nakamura MT, Harasim-Symbor E, Chabowski A, Dyck DJ, Mutch DM. 2023. A reduction of skeletal muscle DHA content does not result in impaired whole body glucose tolerance or skeletal muscle basal insulin signaling in otherwise healthy mice. Am J Physiol Endocrinol Metab; 324 (3): E241-E250.
2022
Rotarescu RD, Rezaei K, Mutch DM, Metherel AH. 2022. Increases in plasma n-3 tetracosapentaenoic acid and tetracosahexaenoic acid following 12 weeks of EPA, but not DHA, supplementation in women and men. Prostaglandins Leukot Essent Fatty Acids; 185: 102494.
Marin-Couture E, Filion MJ, Boukari R, Jeejeebhoy K, Dhaliwal R, Brauer P, Royall D, Mutch DM, Klein D, Tremblay A, Rhéaume C. 2022. Relationship between Cardiometabolic Factors and the Response of Blood Pressure to a One-Year Primary Care Lifestyle Intervention in Metabolic Syndrome Patients. Metabolites; 12 (9): 861.
Brauer P, Royall D, Li A, Rodrigues A, Green J, Macklin S, Craig A, Chan M, Pasanen J, Brunelle L, Dhaliwal R, Klein D, Tremblay A, Rheaume C, Mutch DM, Jeejeebhoy K. 2022. Key process features of personalized diet counselling in metabolic syndrome: secondary analysis of feasibility study in primary care. BMC Nutr; 8 (1): 45.
LeMoire A, Abdelmagid S, Ma DWL, El-Sohemy A, Mutch DM. 2022. Δ5 and Δ6 desaturase indices are not associated with zinc intake as determined by dietary assessment or modified by a zinc-FADS1 rs174547 SNP interaction in young Canadian adults. Prostaglandins Leukot Essent Fatty Acids; 180: 102439.
Wang C, MacIntyre B, Mutch DM. 2022. Inhibition of Δ-6 desaturase reduces fatty acid re-esterification in 3T3-L1 adipocytes independent of changes in n3-PUFA cellular content. Biochim Biophys Acta Mol Cell Biol Lipids; 1867 (7): 159160.
Keathley J, Garneau V, Marcil V, Mutch DM, Robitaille J, Rudkowska I, Sofian G, Desroches S, Vohl MC. 2022. Clinical Practice Guidelines Using GRADE and AGREE II for the Impact of Genetic Variants on Plasma Lipid/Lipoprotein/Apolipoprotein Responsiveness to Omega-3 Fatty Acids. Front Nutr; 8: 768474.
Keathley J, Garneau V, Marcil V, Mutch DM, Robitaille J, Rudkowska I, Sofian GM, Desroches S, Vohl MC. 2022. Nutrigenetics, omega-3 and plasma lipids/lipoproteins/apolipoproteins with evidence evaluation using the GRADE approach: a systematic review. BMJ Open; 12 (2): e054417.
Raman M, Ma C, Taylor LM, Dieleman LA, Gkoutos GV, Vallance JK, McCoy KD, Lewis I, Jijon H, McKay DM, Mutch DM, Barkema HW, Gibson D, Rauch M, Ghosh S. 2022. Crohn’s disease therapeutic dietary intervention (CD-TDI): study protocol for a randomised controlled trial. BMJ Open Gastroenterol; 9 (1): e000841.
Rajna A, Brown LH, Frangos SM, Gonzalez-Soto M, Hucik B, Wang C, Wright DC, Mutch DM. 2022. Plant and marine N3-PUFA regulation of fatty acid trafficking along the adipose tissue-liver axis varies according to nutritional state. J Nutr Biochem; 102: 108940.
Horne JR, Nielsen DE, Madill J, Robitaille J, Vohl MC, Mutch DM. Guiding Global Best Practice in Personalized Nutrition Based on Genetics: The Development of a Nutrigenomics Care Map. 2022. J Acad Nutr Diet; 122 (2): 259-69.
Mutch DM, Lowry DE, Roth M, Sihag J, Hammad SS, Taylor CG, Zahradka P, Connelly PW, West SG, Bowen K, Kris-Etherton PM, Lamarche B, Couture P, Guay V, Jenkins DJA, Eck P, Jones PJH. 2022. Polymorphisms in the stearoyl-CoA desaturase gene modify blood glucose response to dietary oils varying in MUFA content in adults with obesity. Br J Nutr; 127 (4): 503-12.
2021
Maitland SB, Brauer P, Mutch DM, Royall D, Klein D, Tremblay A, Rheaume C, Dhaliwal R, Jeejeebhoy K. 2021. Evaluation of Latent Models Assessing Physical Fitness and the Healthy Eating Index in Community Studies: Time-, Sex-, and Diabetes-Status Invariance. Nutrients; 13 (12): 4258.
Gonzalez-Soto M, Abdelmagid SA, Ma DWL, El-Sohemy A, Mutch DM. 2021. Soy Consumption, but Not Dairy Consumption, Is Inversely Associated with Fatty Acid Desaturase Activity in Young Adults. Nutrients; 13 (8): 2817.
Hucik B, Lovell AJ, Hoecht EM, Cervone DT, Mutch DM, Dyck DJ. 2021. Regulation of adipose tissue lipolysis by ghrelin is impaired with high-fat diet feeding and is not restored with exercise. Adipocyte; 10 (1): 338-49.
Wang C, Murphy J, Delaney KZ, Khor N, Morais JA, Tsoukas MA, Lowry DE, Mutch DM, Santosa S. 2021. Association between rs174537 FADS1 polymorphism and immune cell profiles in abdominal and femoral subcutaneous adipose tissue: an exploratory study in adults with obesity. Adipocyte; 10 (1): 124-30.
Gonzalez-Soto M, Mutch DM. 2021. Diet regulation of long-chain polyunsaturated fatty acid synthesis: role of macronutrients, micronutrients, and polyphenols on δ5/δ6 desaturases and elongases 2/5. Adv Nutr; 12 (3): 980-94.
Metherel AH, Irfan M, Klingel SL, Mutch DM, Bazinet RP. 2021. Higher Increase in Plasma DHA in Females Compared to Males Following EPA Supplementation May Be Influenced by a Polymorphism in ELOVL2: An Exploratory Study. Lipids; 56 (2): 211-28.
2020
Mutch DM. 2020. The Covid-19 Global Pandemic: A Natural Experiment in the Making. Lifestyle Genom. 13 (5): 135-37.
Mutch DM, Dyck DJ. Editorial overview: Musculoskeletal 2020 – adipokines. Curr Opin Pharmacol. S1471-4892 (20) 30025-4.
Horman T, Fernandes MF, Tache MC, Hucik B, Mutch DM, Leri F. 2020. Dietary n-6/n-3 Ratio Influences Brain Fatty Acid Composition in Adult Rats. Nutrients; 12 (6): E1847.
Brown LH, Mutch DM. 2020. Mechanisms underlying N3-PUFA regulation of white adipose tissue endocrine function. Curr Opin Pharmacol; 52: 40-46.
Jannas-Vela S, Klingel SL, Cervone DT, Wickham KA, Heigenhauser GJF, Mutch DM, Holloway GP, Spriet LL. 2020. Resting metabolic rate and skeletal muscle SERCA and Na+ /K+ ATPase activities are not affected by fish oil supplementation in healthy older adults. Physiol Rep; 8 (9): e14408.
Tremblay A, Bélanger MP, Dhaliwal R, Brauer P, Royall D, Mutch DM, Rhéaume C. 2020. Impact of a multidisciplinary intervention on physical fitness, physical activity habits and the association between aerobic fitness and components of metabolic syndrome in adults diagnosed with metabolic syndrome. Arch Public Health; 78: 22.
Lowry DE, Feng Z, Jeejeebhoy K, Dhaliwal R, Brauer P, Royall D, Tremblay A, Klein D, Mutch DM. 2020. Prediction Modelling of 1-year outcomes to a personalized lifestyle intervention for Canadians with Metabolic Syndrome. Appl Physiol Nutr Metab; 45 (6): 621-627.
Townsend LK, Gandhi S, Shamshoum H, Trottier SK, Mutch DM, Reimer RA, Shearer J, LeBlanc PJ, Wright DC. 2020. Exercise and Dairy Protein have Distinct Effects on Indices of Liver and Systemic Lipid Metabolism. Obesity (Silver Spring); 28 (1): 97-105.
Jannas-Vela S, Klingel SL, Mutch DM, Spriet L. 2020. DHA supplementation decreases resting metabolic rate in healthy young females. Appl Physiol Nutr Metab; 45 (2): 221-225.
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